Beyond KRAS(G12C): Biochemical and Computational Characterization of Sotorasib and Adagrasib Binding Specificity and the Critical Role of H95 and Y96

Approved

Classifications

MinEdu publication type
A1 Journal article (peer-reviewed)
Definition
Article
Target group
Scientific
Peer reviewed
Peer-reviewed
Article type
Journal article
Host publication type
Journal

Authors of the publication

Number of authors
12
Authors
Mahran, Randa; Kapp, Jonas N; Valtonen, Salla; Champagne, Allison; Ning, Jinying; Gillette, William; Stephen, Andrew G; Hao, Feng; Plückthun, Andreas; Härmä, Harri; Pantsar, Tatu; Kopra, Kari
Local authors

Publication channel information

Title of journal/series
Acs chemical biology
ISSN (print)
1554-8929
ISSN (electronic)
1554-8937
ISSN (linking)
1554-8929
Publisher
American chemical society
Publication forum ID
50179
Publication forum level
2
Internationality
Yes

Detailed publication information

Publication year
2024
Reporting year
2024
Journal/series volume number
19
Journal/series issue number
10
Page numbers
2152-2164
DOI
10.1021/acschembio.4c00315
Language of publication
English

Co-publication information

International co-publication
Yes
Co-publication with a company
No

Availability

Link to self-archived version
https://erepo.uef.fi/handle/123456789/33178

Classification and additional information

MinEdu field of science classification
116 Chemical sciences, 1182 Biochemistry, cell and molecular biology, 3122 Cancers, 317 Pharmacy

Source database ID

WoS ID
WOS:001314338500001
Scopus ID
2-s2.0-85205058693