Asymmetric Synthesis and Biological Evaluation of Both Enantiomers of 5- and 6-Boronotryptophan as Potential Boron Delivery Agents for Boron Neutron Capture Therapy

We thank Biocenter Finland/DDCB for financial support and the CSC-IT Center for Science Ltd. (Finland) for the allocation of computational resources. M.R.’s research contract (63-G-19602-1) was cofinanced by the European Union “FSE-REACT-EU, PON Research and Innovation 2014–2020 DM 1062/2021” (CUP H31B21009610007). G.P. acknowledges research support by the European Union - NextGenerationEU under the Italian Ministry of University and Research (MUR) National Innovation Ecosystem Grant ECS00000041-VITALITY-CUP H33C22000430006 and Università degli Studi di Urbino Carlo Bo and MUR for support within the project Vitality. J.M.T. thanks the Finnish Cultural Foundation and the Päivikki and Sakari Sohlberg Foundation for funding the research. J.J. thanks the Finnish Cultural Foundation, the Finnish Concordia Fund, the Eino Räsänen Fund, and the Cancer Society of North Savo, Savo Cancer Fund. J.R. thanks the Research Council of Finland for financial support (355312).